Posts filed under ‘User Stories’
Cytobank User Stories: Regina Cheung, Ph.D.
Welcome to Cytobank User Stories, a series featuring interviews with Cytobank users on their research, scientific vision, and use of flow and mass cytometry.
This time we interview Regina K. Cheung, Ph.D., Associate Disease Area Manager (Peripheral Arterial Disease, Obesity, and Stroke) at Cardiovascular Resource Group. Regina performed her doctoral work in the laboratory of Dr. Paul Utz at Stanford Univeristy.
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| What are you excited about in science? What is your scientific vision? |
 Regina K. Cheung, Ph.D. – Cardiovascular Resource Group I love science because it helps us to understand the world around us, and more importantly, the world within us. I originally trained as an engineer, but eventually realized that as much fun as it was to build robots, I am even more fascinated by the conundrum that is understanding how living beings are built. As we unravel how the amazing system that is the human body works, we can use this knowledge to develop therapeutics. (more…) |
Cytobank User Stories: Eric Padron, M.D.
Welcome to Cytobank User Stories, a series featuring interviews with Cytobank users on their research, scientific vision, and use of flow cytometry.
This time we interview Eric Padron, M.D., Clinical Instructor at the H. Lee Moffitt Cancer Center. Dr. Padron is in the laboratory of PK Epling-Burnette in the division of Malignant Hematology.
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| What are you excited about in science? What is your scientific vision? |
 Eric Padron M.D. – Moffitt Cancer Center The genomic age has given investigators an unprecedented window in to the molecular abnormalities within cancer cells. Through this window, we see that there are many molecular abnormalities, some occurring in divergent pathways. As a physician-scientist I am most interested in identifying which of these pathways are required for cancer cell viability/proliferation and leveraging this information for the design of genomically targeted pharmaceuticals in clinical trials. (more…) |
February 28, 2013 at 2:21 pm Angela Landrigan Leave a comment
Cytobank User Stories: Sarah Tasian, M.D.
Welcome to Cytobank User Stories, a series featuring interviews with Cytobank users on their research, scientific vision, and use of flow cytometry.
This time we interview Sarah Tasian, M.D., Attending Physician and Instructor in the Division of Oncology at the Children’s Hospital of Philadelphia. She is part of the Grupp lab and co-mentored by Martin Carroll, M.D. Her recent publications include her work studying STAT5 and PI3K/mTOR signaling in B-precursor acute lymphoblastic leukemia cells (ALL) and studying the effects of JAK and mTOR inhibition in B-precursor ALL mouse xenografts.
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| What are you excited about in science? What is your scientific vision? |
 Sarah Tasian, M.D. – Children’s Hospital of Philadelphia My long-term career goal as a translational physician-scientist in pediatric oncology is to develop better therapies, improve cure rates, and minimize toxicities for children with high-risk leukemias. In the laboratory, I study perturbations of signal transduction networks in genetic subtypes of pediatric B-precursor acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) with the goal of identification of relevant targets for novel targeted therapies. I use specialized immunocompromised murine xenograft models of childhood ALL and AML for the preclinical testing of relevant signal transduction inhibitor (STIs) and of newer chimeric antigen receptor (CAR)-based T cell immunotherapy. I use phosphoflow cytometry to study signal transduction in primary patient leukemia samples and to measure molecular responses to STIs in vitro and in vivo. I am also involved in the testing of STIs in children with relapsed leukemias via Phase I clinical trials through the Children’s Oncology Group. Successful development of these laboratory and clinical research strategies will ultimately allow me to lead a translational research program in developmental therapeutics for children with clinically high-risk leukemias. (more…) |
January 28, 2013 at 6:59 pm Angela Landrigan Leave a comment
Cytobank User Stories: Bernd Bodenmiller, Ph.D.
Welcome to Cytobank User Stories, a series featuring interviews with Cytobank users on their research, scientific vision, and use of flow cytometry.
This time we interview Bernd Bodenmiller, Ph.D., Group Leader in Systems Biology at the Institute of Molecular Life Sciences at the University of Zurich. His recent publications include his work using mass cytometry to profile cellular states perturbed by small-molecule regulators, as well as his contributions towards developing a viability reagent for mass cytometry. Both of these datasets are publicly available via Cytobank:
Cytobank Report: Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators
Cytobank Report: A platinum-based covalent viability reagent for single cell mass cytometry
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| What are you excited about in science? What is your scientific vision? |
 Bernd Bodenmiller, Ph.D. should strive to develop novel analysis technologies, as they have the power to trigger new research fields. My vision? I would love to see non-invasive measurement technologies like in Star Trek to scan a person and allow us to determine a health profile within seconds. Sounds crazy, isn’t it? But when Star Trek the original series was aired the first time, everybody thought it was “science fiction” that Spock and colleagues used little devices that fit into their hands to talk to each over long distances and to retrieve information. Now nearly everyone has one of these… |
November 30, 2012 at 2:09 pm Angela Landrigan Leave a comment
Cytobank User Stories: Erin Simonds, Ph.D.
Welcome to Cytobank User Stories, a series featuring interviews with Cytobank users on their research, scientific vision, and use of flow cytometry.
This time we interview Erin Simonds, Ph.D., a Postdoctoral Scholar in the W. A. Weiss Lab in the Department of Neurology at the University of California San Francisco. His recent publications include his work on mass cytometry to study human hematopoietic cells, as well as his work developing a viability reagent for mass cytometry. Both of these datasets are publicly available on Cytobank:
Cytobank Report: Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
Cytobank Report: A platinum-based covalent viability reagent for single cell mass cytometry
Send us feedback and let us know who you’d like to hear from (including yourself)!
| What are you excited about in science? What is your scientific vision? |
 Erin Simonds, Ph.D. (W.A. Weiss Lab – UCSF) (more…) |
October 30, 2012 at 4:57 pm Angela Landrigan Leave a comment
Cytobank User Stories: Anders Egeland
Welcome to Cytobank User Stories, a series featuring interviews with Cytobank users on their research, scientific vision, and use of flow cytometry.
This time we interview Anders Egeland, a medical student in the Taskén group at the The Biotechnology Center of Oslo at the University of Oslo.
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| What are you excited about in science? What is your scientific vision? |
 Anders Egeland, University of Oslo Science is exciting as it’s full of unsolved questions, and answers to some of these questions can often be translated into therapies in the long term. As an ever-increasing body of knowledge continues to accumulate within the medical domain, more advanced methods from other research fields such as mathematics and physics are needed to understand the complex biological relationships. I aim to combine these fields to gain new insights. Hopefully, in the future MDs will be able to use these computational techniques, e.g. SPADE provided by Cytobank, in the clinic when they assess the clinical status of a patient. |
September 21, 2012 at 8:28 am Angela Landrigan Leave a comment
