Top Trends, Presentations, and Takeaways from CYTO 2018

CYTO, the International Society for the Advancement of Cytometry (ISAC)’s annual meeting wrapped up earlier this month in the exciting city of Prague, Czech Republic. As the premier meeting for showcasing the state of the art and science of cytometry, CYTO and its members revealed no small number of exciting developments in cytometry and beyond. We’re just now getting around to sharing all we saw and heard at the meeting. Some of our favorite presentations and observations include: More »

May 25, 2018  |  Education, Events, viSNE, Webinars

Webinar Recap: Advanced viSNE (t-SNE) Review

Untitled-1Nearly 500 scientists registered for our latest data analysis webinar. Cytobank Application Scientist Geoff Kraker took us on a tour of recently added features like setting the seed (for replicating results), configuring display gate labels, and more. If you missed it, not to worry. The recording is now available online.

cyobankarrow40x40View our latest webinars on the Cytobank YouTube channel

Following the demo, Geoff fielded many great live questions from the viewers. Here are some of our favorites: More »

April 30, 2018  |  Education, Events, viSNE, Webinars

May Webinar: New Developments in viSNE Presented by Geoff Kraker

If you missed the webinar, click here to view the recording on our YouTube Channel.

Join us for our free Webinar May 17, 2018 9:00 AM PDT/ 16:00 GMT

In our previous and popular webinars featuring viSNE, hundreds have logged on to watch as scientists showed us how they used viSNE to make discoveries in the clinic and build comprehensive data analysis pipelines for their high parameter data.

With recent improvements released on Cytobank, it’s a great time to gather and review viSNE best practices, to dive deeper into how you can now explore your data more efficiently with viSNE, and how you can extend viSNE’s capabilities by integrating with other analysis approaches, including basic analysis and more advanced machine learning algorithms.visne_display_gates More »

April 16, 2018  |  Conferences, Events, viSNE

AACR Bulletin: Don’t Miss our Booth, Key Presentations in Chicago

cytobankbooth3603If you’re at the Annual Meeting of the AACR (American Association for Cancer Research), come visit our team in person, get some hands-on help, and see the latest developments in how our cloud-based Machine Learning analysis platform can help accelerate more detailed discovery.
Meet us at Booth #3603
.

Posters and Talks:

We’re excited to see the breadth and depth of presentations throughout the conference program that include work done on the Cytobank platform. In addition to our very own team’s presentation on rapid RNA-seq biomarker discovery, many others have used of Cytobank in their discoveries. See here for a sampling of posters and talks submitted to us by our users. More »

April 11, 2018  |  Announcements, Conferences, Flow Cytometry

Announcing Cytobank’s Collaboration with Cytek Biosciences

We’rCytekLogoe excited to announce a new collaboration with Cytek, makers of the innovative CytekTM Aurora Flow Cytometer. Cytek’s Aurora and Cytobank’s next-generation analytics platform have united in their goal to make high-dimensional data and its subsequent machine learning analysis more accessible to more scientists.

  • Aurora’s unique optical design combined with spectral unmixing delivers quality, high-dimensional data where rare and dim populations can be easily resolved, regardless of sample complexity.
  • Cytobank’s algorithms simplify visualization and analysis of high-dimensional unmixed data and allow you to quickly share discrete insights from these data.

Here are two specific examples of how you can apply our combined solutions to enable faster, more highly-resolved discoveries: More »

December 20, 2017  |  Conferences, viSNE

ASH Annual Meeting Report: Key Takeaways and Developments

We were excited to attend the American Society of Hematology meeting this month in Atlanta. Despite the conference beginning with the arrival of an unexpected winter storm, many leading scientists and clinicians congregated to present and discuss cutting-edge research in hematology.

The Cytobank platform was used by many who attended and presented and we were proud to contribute to these scientific advances. Highlights for us were:

  1. A multiparametric approach, “pharmacoscopy:” (a single-cell drug-response profiling approach that utilizes IF, automated microscopy, and image analysis, as detailed by Vladimer, Snijder et al., Nat. Chem. Biol. 2017) identified targetable drug pathways in CLL patients. Interestingly, the way that these authors use image morphology to quantify cell death is similar to what Ross Marklein from the FDA’s Center for Biologics Evaluation and Research (CBER) presented at BMES using Cytobank on imaging morphology data. In our consulting services, we’re excited to work with our customers on projects that integrate multiple data types, such as this work presented at ASH.
  2. Next Generation Sequencing (NGS) and its application in the clinic today was widely discussed. Similar to high dimensional cytometry analyses, developing reproducible and efficient bioinformatics analysis pipelines was identified as a major challenge to dissecting the large volume of data generated by NGS. During the late breaking abstract session, Dr. Tim Grob, presented data from a large prospective clinical trial demonstrating that NGS MRD detection can predict relapse and survival in newly diagnosed AML.
    Challenges for clinical use of Whole Exome Sequencing presented by Dr. Haferlach
    Challenges for clinical use of Whole Exome Sequencing presented by Dr. Haferlach.

     

  3.  Cytobank in action: Numerous posters and presentations used Cytobank to investigate immune system response to cancer, dysplasia, and other blood disorders. Some examples include:

20171210_TanayaShree_presenting_Stanford-1600px
Tanaya Shree, Stanford University Medical Center, presenting “
Altered Peripheral Immune Phenotypes in Mantle Cell Lymphoma Survivors”. Here, CITRUS helped identify alterations of T cell subsets on MCL PBMC samples as compared to healthy donor samples.

20171211_IbrutinibInhibitscGVHDPathogenicPre-GerminalCenterBcellsandTfh-1600px
Bita Sahaf:
“Ibrutinib Inhibits cGVHD Pathogenic Pre-Germinal center B-cells and Follicular Helper Cells While Preserving Immune Memory and Th1 T-cells”

20171210_ThomasCoats_King'sCollegeLondon-1600px
Thomas Coats:
Neoantigens in MDS Are Associated with Two Novel CD4+ T Cell Subsets and Improved Overall Survival”

Learn more about how you can: