Author Archive

Cytobank User Stories: June Myklebust, Ph.D.

Welcome to Cytobank User Stories, a series featuring interviews with Cytobank users on their research, scientific vision, and use of flow cytometry.

This time we interview June Myklebust, Ph.D., a project leader in Erland Smeland’s lab at Oslo University Hospital and former postdoctoral fellow in the Levy Lab at Stanford. June’s recent publications include her contributions to studies on B-cell signaling networks in lymphoma and her work on bone morphogenetic proteins in B cell suppression.

Send us feedback and let us know who you’d like to hear from (including yourself)!

What are you excited about in science? What is your scientific vision?

June Myklebust, Ph.D.
Project Leader, Smeland lab
Oslo University Hospital

New discoveries that change our current biological models or change our view of what can be done in terms of therapeutic options. My scientific goal is to make discoveries from which patients can benefit. One of the challenges in cancer therapy today is to understand the molecular mechanisms for how patients develop fatal drug resistance. In the era of personalized medicine, development of in vitro assays with predictive power for drug-responsiveness, which then can guide the choice of therapy, would also be highly beneficial. I believe the ability to detect tumor cell heterogeneity will be crucial to address these issues, and therefore platforms for large-scale single cell measurements likely will be tiebreakers.

(more…)

February 21, 2012 at 10:45 am Leave a comment

Cytobank User Stories: Sean Bendall, Ph.D.

Welcome to our inaugural issue of Cytobank User Stories, a series featuring interviews with Cytobank users on their research, scientific vision, and use of flow cytometry.

First up is Sean Bendall, Ph.D., a postdoctoral fellow in Garry Nolan’s lab at Stanford University. Sean’s recent publications include his work on mass cytometry as well as SPADE (available in hosted models of Cytobank).

We’d be happy to hear what you think. Send us feedback and let us know who you’d like to hear from (including yourself)!

What are you excited about in science? What is your scientific vision?

Sean Bendall, Ph.D.
Postdoctoral fellow, Nolan lab
Stanford University

The thought of finding new biological paradigms is what gets me most excited.  There are many basic things in life that happen (biologically / biochemically – that is) which we take for granted.  However the underlying mechanism of many of these is completely unknown to us, and thus when they go awry we have little recourse to address them therapeutically.  Currently, in the context of the human genome, we really only have a grasp on about 20% of what’s there.  My overriding goal would be to develop methods / systems to help rapidly fill in this knowledge gap.  Because of the complexity (heterogeneity) of the human system, I believe that single-cell approaches will be best in addressing this and therefore my work will only put an increasing demand on analysis platforms to accommodate it.

(more…)

January 23, 2012 at 10:33 am Leave a comment

Introducing the Newly Redesigned Cytobank Support Portal

If you’ve clicked the “Support” link at the top of the Cytobank webpage, you may have noticed that our support portal has a new look and some new features.

Search our Knowledge Base

Our new support site has a Knowledge Base filled with articles to augment your Cytobank experience. You’ll find tutorials on our functionalities using real datasets, articles guiding you in both basic and advanced Cytobank usage, and answers to frequently asked questions. You can browse through article sections or conduct a keyword search of the Knowledge Base.

What kind of support can I receive from Cytobank?

We offer a wide range of support for your flow cytometry endeavors:

  • One-on-one WebEx-based training to get you started using Cytobank
  • Biology consulting support: How to design experiments, what to measure, selecting reagents, how to build figures, how to share datasets from your peer-reviewed publications
  • Troubleshooting
  • Data security
  • Technical support for networks
  • Inquiries about getting started with premium functionalities such as SPADE and dose response

(more…)

January 21, 2012 at 9:43 pm Leave a comment

Getting Your Lab Organized on Cytobank

With a new year ahead of us, you might be thinking it’s time for a fresh start. Maybe it’s time to organize the experiments that resulted from a flurry of work at the end of last year, or maybe you manage a lab and would like to keep past and ongoing experiments organized as people join and leave the lab. In this post, we’ll share our thoughts on how Cytobank can help you achieve these goals.

Hosted models of Cytobank

You may be familiar with our main server at http://www.cytobank.org/cytobank/, but did you know that we can host an instance of Cytobank specifically for your lab group? With these hosted solutions, your lab manager or PI controls who has access to your server and can guide the group in configuring projects to keep various research branches well organized. Read our previous post on Projects to learn more about Projects. Hosted models of Cytobank also have the advantage of offering you premium functionality that isn’t available on our main server, such as SPADE and dose response.
(more…)

January 21, 2012 at 12:04 pm Leave a comment

Highlights of the Cytobank Blog

As the end of 2011 approaches, we thought we’d take this opportunity to highlight posts from earlier days.

The Cytobank Story – Read about how the need for dynamic summaries of experiment results linked to the underlying single cell data resulted in the creation of Cytobank.

 

Cytometry in the Cloud – Advances in flow cytometry now enable researchers and clinicians to simultaneously measure a large number of cellular parameters. Learn about how doing cytometry in the cloud with Cytobank can accelerate data analysis, foster collaboration, and provide data back-ups.

Mass Cytometry: Vaporizing Cells in the Name of Science – Learn about mass cytometry, where antibodies are conjugated to element isotopes instead of fluorphores, increasing the number of cellular parameters that can be assayed in one sample tube. Access the raw data from a Nolan lab dataset published in Science this year, and try your hand at analyzing mass cytometry data yourself!
(more…)

November 30, 2011 at 12:10 pm Leave a comment

Clear the Clutter: Organize Your Experiment Inbox

You probably don’t intend your experiment inbox to be a frenzied mess of experiments resembling your lab bench after a long night at the flow cytometer. Luckily, we have provided you with a number of tools that give you the power to efficiently manage your experiment data. In this post, we’ll highlight some of these methods of organizing and filtering your experiments. Consider this a supplement to our previous post on Future-Proofing Your Data!

Public experiments and Archived experiments are flagged with "P" or "A," respectively.

The Experiment Inbox is the first page on which you land when logging into Cytobank. By default, you will see “All Experiments,” including public experiments (denoted with a ‘P’), experiments you uploaded, experiments shared with you, and your archived experiments (marked with an ‘A’). You can change your default inbox view on your Profile page (click the Profile link at top of the experiment inbox, and then click “Edit”), for example if you wanted to display only “My Experiments” every time you log in.
(more…)

November 30, 2011 at 11:40 am 1 comment

Older Posts


Recent Posts

@Cytobank

Enter your email address to subscribe to the Cytobank blog and receive notifications of new posts by email.

Join 9 other followers